By Balveer Singh Rathore, Editor · Last updated: September 25, 2026 · How we write
Relaxium Sleep is a dietary supplement that combines 5 mg of melatonin with magnesium, ashwagandha, L-tryptophan, GABA, chamomile, passionflower and a branded blend called Valerest. Some of these ingredients may help some people fall asleep, but we found no published, peer-reviewed trial of the full formula. For ongoing insomnia, doctors recommend cognitive behavioural therapy for insomnia (CBT-I) first.
Our verdict: not our first pick. It may be worth discussing with your doctor for occasional sleeplessness, but it stacks several active ingredients, and some of them interact with common medicines. Start with the sleep habits below and get checked if poor sleep lasts for weeks.
This article is general information, not medical advice. If you have a health condition, are pregnant or take medication, talk to your doctor before changing your diet, exercise or supplements. Read our disclaimer.
Affiliate note: this page may contain an Amazon link. If you buy through it, we may earn a small commission at no extra cost to you. It doesn’t change our verdict. Read our affiliate disclosure.
What is Relaxium Sleep?
Relaxium Sleep is sold in the US by American Behavioral Research Institute (ABRI) as a “drug-free” sleep aid. The brand says it was developed by a clinical neurologist, Dr. Eric Ciliberti. It’s sold online, on TV and through retailers such as Amazon and Costco, as capsules and in other versions such as gummies. Formulas differ between versions, so always read the label of the exact product you’re buying.
Relaxium Sleep ingredients
These are the ingredients and amounts listed on the brand’s ingredients page for the capsule formula (per serving). The evidence and safety notes are based mainly on the U.S. National Institutes of Health resources listed under Sources.
| Ingredient | Amount | What the evidence says | Safety notes |
|---|---|---|---|
| Melatonin | 5 mg | Can help with jet lag and some circadian sleep problems. Not enough strong evidence to recommend it for chronic insomnia. | Headache, dizziness, nausea, next-day sleepiness. Ask a doctor if you take blood thinners or have epilepsy. |
| L-Tryptophan | 500 mg | Limited data. A 2017 clinical guideline advised against it for chronic insomnia. | Can cause serious serotonin toxicity with antidepressants and other medicines that affect serotonin. |
| Valerest® (branded blend) | 228.9 mg | The brand cites a university study but doesn’t give details. Valerian, the herb it’s linked with, hasn’t been shown to work for insomnia. | Valerian: usually mild side effects; long-term safety unknown. |
| Ashwagandha extract | 125 mg | Some preparations may help stress and insomnia, but studies are small. | Avoid in pregnancy, breastfeeding, thyroid or autoimmune conditions. Rare liver injury reported. |
| Magnesium (citrate, glycinate, oxide) | 100 mg | Evidence for sleep is limited. | Can cause loose stools. |
| GABA | 100 mg | Little good evidence that oral GABA improves sleep. | Limited safety data. |
| Chamomile extract | 75 mg | No conclusive clinical evidence for insomnia. | Allergy risk, especially if you’re allergic to ragweed. |
| Passionflower extract | 75 mg | Small, early studies only. | May cause sleepiness or dizziness, and may add to the effect of sedatives. |
Does Relaxium Sleep work?
We couldn’t find any published, peer-reviewed human trial of the complete Relaxium Sleep formula. The brand’s claims rely on research into individual ingredients and on a Valerest study that isn’t described in detail.
In April 2025, the U.S. Food and Drug Administration (FDA) sent ABRI a warning letter. The FDA said the company had run a clinical study of Relaxium Sleep for insomnia (40 participants) without the required Investigational New Drug application, and that this “raises concerns about the validity and integrity of the data collected.” That means results from that study should be treated with caution.
Online customer reviews can’t settle the question either. Sleep often improves on its own, and placebo effects are common in sleep research, so individual stories don’t show whether the capsule made the difference.
Relaxium Sleep side effects
- Next-morning grogginess or sleepiness. Don’t drive until you know how it affects you.
- Headache, dizziness, nausea or stomach upset.
- Allergic reactions (chamomile and other plant extracts).
- Stronger effects if taken with alcohol, sleeping pills or other sedatives.
Who should not take it without a doctor’s OK
- People taking antidepressants or other medicines that affect serotonin (because of L-tryptophan)
- People on blood thinners or with epilepsy (melatonin)
- Anyone pregnant or breastfeeding
- People with thyroid disease, autoimmune conditions or liver problems (ashwagandha)
- Children and teenagers
- Anyone taking sleeping pills, anti-anxiety medicines, diabetes or blood pressure medicines
Is Relaxium Sleep safe?
For most healthy adults, short-term use is unlikely to cause serious harm, but “drug-free” doesn’t mean risk-free. Supplements aren’t approved by the FDA for safety or effectiveness before they’re sold. Independent testing has also found that many melatonin products contain more or less melatonin than their labels say. Combining several sleep-affecting ingredients raises the chance of side effects and interactions, so check with a doctor or pharmacist first, especially if you take any regular medicine.
Better first steps for sleep problems
- Keep a fixed wake-up time, even on weekends.
- Get daylight in the morning and dim screens and lights in the hour before bed.
- Cut caffeine after lunch and avoid alcohol close to bedtime.
- Keep your bedroom cool, dark and quiet.
- If you can’t sleep after about 20 minutes, get up and do something calm until you feel sleepy.
- Ask about CBT-I. The American College of Physicians recommends cognitive behavioural therapy for insomnia as the first treatment for chronic insomnia. It’s available in person and through apps and online programmes.
- See a doctor if poor sleep happens three or more nights a week for weeks, or if you snore loudly, stop breathing in your sleep or feel very sleepy in the day.
Regular exercise also helps many people sleep better. See our simple home workout plan and everyday health and fitness tips.
If you and your doctor decide to try Relaxium Sleep, note that we could not find it listed on Amazon India (checked 27 September 2026), so buy only from an authorised seller. Start with the lowest suggested amount and don’t combine it with other sleep aids.
Frequently asked questions
Does Relaxium Sleep really work?
There’s no published, peer-reviewed trial of the complete Relaxium Sleep formula. Melatonin can help some circadian sleep problems, and some ashwagandha preparations show modest benefits, but evidence for the other ingredients is weak. In 2025 the FDA also raised concerns about how the company ran its own insomnia study.
What are the ingredients in Relaxium Sleep?
The capsule formula lists melatonin (5 mg), L-tryptophan (500 mg), the Valerest® blend (228.9 mg), ashwagandha (125 mg), magnesium (100 mg), GABA (100 mg), chamomile (75 mg) and passionflower (75 mg) per serving. Gummies and other versions have different formulas, so check the label of the product you buy.
What are the side effects of Relaxium Sleep?
Possible side effects include next-day grogginess, headache, dizziness, nausea, stomach upset and allergic reactions. L-tryptophan can cause dangerous serotonin toxicity with some antidepressants, and melatonin needs caution with blood thinners and epilepsy. Avoid alcohol and other sedatives with it, and don’t drive until you know how it affects you.
Is Relaxium Sleep safe to take every night?
Long-term safety of the full formula hasn’t been studied. Ashwagandha is considered possibly safe for up to about three months, and melatonin’s long-term effects are unclear. If you feel you need a sleep aid every night, speak to a doctor. Ongoing insomnia is better treated with CBT-I and by checking for underlying causes.
Is Relaxium Sleep FDA approved?
No. Relaxium Sleep is sold as a dietary supplement, and supplements don’t need FDA approval before they’re sold. In April 2025 the FDA sent the maker a warning letter for testing the product as an insomnia treatment without the required Investigational New Drug application.
Can I take Relaxium Sleep with antidepressants?
Not without your doctor’s approval. Relaxium Sleep contains L-tryptophan, which the NIH warns may cause life-threatening serotonin toxicity when combined with medicines that affect serotonin, such as many antidepressants. Show the full ingredient list to your doctor or pharmacist before taking it.